(1) Feed protein allows expressing genetic potential in poultry and pigs. Its content must be balanced with the others ingredients and with the digestive capacity of the animals.

(2) The protein contributes essential and non-essential amino acids and energy (practically the same as that of carbohydrates), to foods, which are used in constituting tissues and in maintaining essential vital functions.

(3) There is currently, among some nutrologists, the tendency to reduce the protein for various reasons:

• Environmental.
• Restrictions on the use of antibiotics and OZn in feed that prevent fermentation of excess protein and non-digestible protein from of raw materials with low bioavailability.

(4) The restrictions on the use of antibiotics started, many years ago, to preserve some antibiotics as therapeutic arsenal in human medicine and more recently for environmental purposes.

(5) The restrictions on the use of OZn are more recent and are based on studies that defend that it increases bacterial resistance, reduces the effect of some enzymes, copper absorption and the effect of acidifying agents. Consequently its pharmacological use in feed is prohibited and its nutritional use is restricted in the EU and extending to other areas such as China.

(6) Either for environmental reasons or because of the difficulty of using antibiotics and OZn, some nutrologists are opting to reduce the protein level in feed, causing some undesirable effects:

• Reduced growth.
• Increased consumption and loss FRC.
• Increase in fat in the carcass, especially abdominal fat.
• Reduction of % of breast in carcass.

(7) The negative effects on the growth and quality of the carcass, due to the reduction of protein, have been able to palliate by increasing the energy of the feed (fats), adding synthetic amino acids (lysine, methionine and threonine), organic acids (propionic, formic), activated diatoms (A.Diatom) and pronutrients (Alquernat)

(8) Our investigation using organic acids shown that the addition of ammonium propionate and formate (Liquid Alquermold) improved the conversion rate by 2%.

(9) We have shown that the use of activated diatoms (A.Diatom) also alleviates protein reduction by increase its digestibility in poultry by 4.26%.

(10) Biovet‘s research on the use of pronutrients began in 1997 in several countries in Asia and Europe. In 2005 we presented the results at the “Use of Pronutrients in Veterinary” conference at the royal academy of veterinary sciences. From 2005 to 2014 the trials were extended to China and America, including the USA, and the results were presented at the conference “From Proplasts to Pronutrients” at the Peruvian Academy of Veterinary Sciences and we continue to research today.

There are many studies, which are at your disposal, but for this note we have selected some data:

10.1 At the tissue culture level:
– Better vitamin absorption by cell cultures of enterocytes
– B12 + 29.97% (B1 + 55.94%) (E 39.02%) (A 43%)
– Better absorption amino acids
– Lysine + 3.87% (tryptophan + 5.3%)

10.2 At histological level:
– Shorter enterocyte renewal time
– Increased villi number
– Increased villi depth

10.3 Pronutrients on the Broiler farm vs Antibiotics:
– Conversion rate 1.52 vs 1.56 Experimental
– Conversion rate 1.72 vs 1.97 g. Comercial
– Weight………2,175 kg vs 1,972 kg
– Carcass……..80.28 % vs 79.23 %.
– Carcass fat……1.06% vs 1.37%
– Breast…………20.59% vs 19.82

10.4 Pronutrients in laying poultry farm:
– Increase in haugh units by 1.9 points.

10.5 Pronutrients in Pig vs OZn:
– Using Nebsui at 0.5 kg/mt and o.zn 3000ppm
– In the first stage and 2500 in the last stage
– 2.86% more lot weight A. Nebsui over OZn
– 3.47% improved conversion index vs OZn.

(11) Biovet, S.A. has investigated a line of products of botanical origin, since 1997, anticipating the needs and evolution of animal nutrition, very pressured by environmental considerations and restrictions on the use of various groups of additives, together with the need to keep intact the expression of the genetic potential of birds and pigs.

These investigations were disclosed in academies of veterinary sciences, obtained the endorsement of various patents and product registration, in many countries, under the scientific name “Pronutrient” and trade names Alquernat for farm animals and Naturbalance for pets.

(12) Pronutrients are products, of botanical origin, which are intended to improve organic physiology and which can be used together, with other additives, in dual programs, or alone, substituting groups of additives, depending on the target cells.

(13) Pronutrients intestinal conditioners are marketed under the name Alquernat Nebsui improve the renewal of the digestive mucosa by reducing the adhesion of pathogenic bacteria to the intestinal surface, improving the production of intestinal endoenzymes and the absorption of nutrients. They are molecules from plants included in the lists of additives of the EU, USA, China and Japan.