Use of cimenol for Pseudomonas spp control in the gut

Pseudomonas is an aerobic Gram-negative bacterium that belongs to the family Pseudomonadaceae, which is composed with more than 140 described species.
These species have demonstrated a great metabolic diversity and are capable of processing and reacting to a wide variety of environmental changing conditions. Some strains are even resistant to heavy metals, organic solvents and detergents, which enables them to use a huge range of carbon sources as well as nutrients and colonize environments that are hardly colonizable for other microorganisms.
Because of this widespread occurrence, they are easily present in water and plant seeds and are, consequently, an important threat for animal production.
One important aspect in their prominence as pathogens is the intrinsic resistance to antibiotics, biocides and disinfectants. The low susceptibility to antibiotics is attributable to having a genomic sequence that includes antibiotic resistance genes and also to the low permeability of the bacterial cell envelopes.
Pseudomonas can be responsible for several diseases including infectious toxic hepatoenteritis, specific infectious coryza, aerosaculitis and some arthritis, as well as subclinical diseases that also affect productive parameters negatively.
Target
In a study conducted in Mexico, a product based on cimenol was tested at different concentrations to prove its effectiveness against Pseudomonas.
Treatments and results
Pathogen | Product concentration | Results (% of CFUs reduction)* |
Pseudomonas spp (CFU/ml) |
Direct |
≥99.999 % |
50 ppm |
99.354 % |
|
500 ppm |
98.963 % |
|
750 ppm |
99.000 % |
|
1000 ppm |
99.524 % |
*% of reduction within 30 seconds of product application to an inoculum of 82 x 109 CFU/ml
Conclusions
Cimenol-based product reduced 99% of Pseudomonas contamination, even when applied at a low dose of 50 ppm, within only 30 seconds of application.
This cimenol-based product is available under the trademark Alquermold Natural L, by Biovet, S.A.
Image: Pseudomonas aeruginosa. Janice Haney – PHIL #10043