9. Use of pronutrients for hepatic regeneration in poultry
Toxic substances in feed, drinking water or in some drugs can be harmful for the liver and alter the liver and kidney metabolism.
This damage causes alterations in the serum biochemical parameters, like the hepatic and renal enzymes, the proteinemia and the glycemia.
Proteinemia is tightly related with antibody production and the synthesis of muscle (meat). For this, the study of the restoration of the plasmatic levels by using liver conditioner pronutrientsÂ is a subject of great interest in poultry.
The present study analyzed pronutrients efficiency to restore proteinemia in broilers suffering from a liver disorder.
Aflatoxin B1-contaminated feed was administered at 2 ppm in feed from day 1 to 10 of age. Then, feed was replaced by a non-contaminated one until day 42. Blood samples were taken on day 11 and 42 to analyze proteinemia as an indicator of liver damage and regeneration, respectively. An increase in proteinemia on day 42 is indicative of a better regeneration of the liver functioning.
Proteinemia results are expressed in grams per 100 mL of plasma.
Group 1 showed a normal evolution for proteinemia according to the age of the animals.
Group 2 showed low proteinemia because of the liver damage on day 11. Despite feed was not contaminated from day 11 to day 42, proteinemia did not improve because the hepatic disorder persisted.
Group 3Â showed a lower proteinemia because of the liver damage on day 11, but protein concentration increased on day 42 thanks to the administration of pronutrients, which proves their liver regenerative effect.
Liver conditioner pronutrients are marketed under the commercial name Alquernat Livol, by Biovet, S.A.