Biotin or vitamin B7 used by birds and mammals can be of exogenous or endogenous origin produced by the animal’s microbiota (bacteroids and proteobacterias)

Regardless of its origin, biotin is consumed in competition between animals and other bacteria of the intestinal microbiota, especially Bifidobacterium, Lactobacillus and Ruminococcus.

Thus, biotin deficiency can cause changes in the microbiota (dysbiosis) and deficiencies in the external and internal epithelia of the animal (plantar, intestinal, respiratory and reproductive) and in the phaneros (hooves, hair and feathers).

As a consequence of the affection of the intestinal epithelium, it can cause loss of consistency of the intracellular junctions (tight junctions), develop a malabsorption syndrome (which leads to deficiencies in the production of meat, eggs and milk) and rapid transit problems.

As a consequence of the affection of the respiratory epithelium, the permeability to the entry of viruses and bacteria into the pulmonary parenchyma can increase.

Because of the affection of the reproductive epithelium, it can increase the permeability to the entry of microorganisms and decrease the quality of the surface where the fertilized ovules nest in mammals.

As a consequence of the condition of the phaneros, especially hooves, the permeability to the entry of bacteria, capable of developing lameness and arthritis, can increase.

Biotin can be use with intestinal conditioner pronutrients. The biotin with intestinal conditioners pronutrients it is available in the Biovet product marketed as Aval-9.