(1) The prohibition or restriction of the use of coccidiostats and antibiotics that promote growth requires the implementation of new strategies to control dysbiosis and derived processes.

(2) The processes derived from dysbiosis, although apparently disconnected, actually constitute a chain ​​of events with progressive degradation of the intestinal status, which may end in a pathological process.

(3) The consequences of dysbiosis are presented, following a certain chronological order, at different levels:

3.1 Decrease in productive parameters

3.2 External symptoms

3.3 Microscopic changes in the digestive mucosa

3.4 Macroscopic changes in the digestive mucosa

3.5 And finally settlement, on the mucosa, of micro-organisms and protozoa.

(4) The main consequences of dysbiosis, the derived processes and their solutions are:

4.1 Productive parameters

The worst data of conversion rate, reduced growth, reduced laying and reduced fertility can be reduced by improving the quality of feed ingredients (bioavailability) and avoiding mycotoxins and antinutritional factors.

4.2 External symptoms

Rapid transit and non-specific diarrhea can be reduced using biosilicates and enzymes.

4.3 Microscopic alteration of the mucosa

It is manifested by reduction in the size of the intestinal villi, reduction in the number of intestinal villi and involvement of the tight junctions between enterocytes. These changes, only observable through microscopy techniques, can be reduced by incorporating pronutrients, intestinal conditioners, which allow the mucosa to regenerate in a period between 3 and 5 days.

4.4 Macroscopic alteration of the mucosa

Macroscopic alterations may manifest macroscopically, to different degrees, up to situations of intestinal fragility, breaking easily during necropsies and by defoliation of the mucosa which appears translucent.

The defoliation and loss of the mucosa can be alleviated by incorporating intestinal conditioner pronutrients that allow the regeneration of the mucosa within a period between 7 and 9 days.

4.5 Micro-organisms/protozoa intervention

Finally, the intestinal mucosa may be invaded by bacteria, viruses and protozoa, through weak tight junctions or lesions with absence of epithelium.

Getting to this situation should be considered a double failure and resorting to the use of drugs a triple failure: not correcting the dysbiosis and its consequences, economic losses for the company (poultry, livestock and aquaculture) and having to apply medications which could have been avoided.

(5) To improve animal welfare, Biovet has investigated a series of products:

5.1 To avoid the presence of mycotoxins (A.ANTITOX)

5.2 To reduce rapid transit (A.DIATOM)

5.3 To improve digestibility (ALQUERZIM)

5.4 Macroscopic and microscopic repair of the mucosa with intestine conditioners (ALQUERNAT NEBSUI)

5.5 Stimulation of the immune physiology of the mucosa, with intestinal optimizer (A.ZYCOX)

5.6 To regenerate the intestinal microbiota (ALQUERFEED BIOTA)

(6) Biovet S.A. has developed this line of six products for intestinal welfare in collaboration with universities in the USA, Europe and Latin America and exposed the results at APCV, RACVE and BIOVET INTERNATIONAL SYMPOSIUM.

(7) The staged use of these 6 products for the intestinal welfare allows the design of a new strategy that avoids serious losses to companies (poultry, livestock and aquaculture) and improves the welfare of animals.