Alternative to orgĂ nic acids: Why do we need ?
In the last three blogs we have talked about preservatives and preservation methods in food, feed and raw materials, and more or less directly about cimenol ring opposite of organic acids used as preservatives. In the present article weâ€™ll run a little bit deeper searching for the differences between both and finally find advantages in the use of cimenol.
Organic acids mechanism of action
So why do we actually need a good alternative to organic acids when used as preservatives in feed? For three reasons:
- Organic acids are corrosive, and so they may damage machinery and have a dangerous handling.
- Some microorganisms restart growing up after certain time because they are able to:
*recycle organic acids as an energy supply (by incorporating them to Krebs cycle) and restore pH, what allows microorganisms to grow and reproduce.
*activate genetic expression of certain decarboxylase, enzymes to increase intracellular pH, which restores growth capability.
As a consequence of these two facts, we can say that:
ORGANIC ACIDS LOSE EFFICIENCY AS TIME GOES BY.
- Every acid has specific range of action and it is only effective over a group of microorganisms.
Thus, we can say that:
ONE ORGANIC ACID CANNOT PROTECT AGAINST ALL POSSIBLE CONTAMINATIONS.
How microorganisms are able to recycle organic acids by Krebs cycle?
Krebs cycle (also called tricarboxilic acids cycle or citric acid cycle) is a very important metabolic cycle for aerobic organisms, cause it is the conjunction ring of metabolic routes related to degradation and disassimilation of carbohidrates, fat and proteins into carbon dioxide and water, producing chemical energy.
Krebs cycle is a metabolic route which takes part in both anabolic and catabolic processes.
This cycle provides lots of supplies to some aminoacid production like cetoglutarate and oxalacetate, as well as other essential molecules for the cell.
Krebs cycle in aerobic fungus and bacteria uses C-C-C carbon chains and oxigen to produce energy (with liberation of carbon dioxide and water) and this is how organic acids are metabolized losing antifungus-antibacteria effects, and so they turn to fungustatic-bacteriostatic, opposite to phenol rings, which donâ€™t get included into Krebs cycle.
â€ś In vitro â€ś test with Cimenol Ring. Feed Preservation Trial.
Place: Microbiology Research Centre in Ireland.
Date: March 2012.
Objective: the core objective of this research study was to determine the capability of cimenol ring to perform feed preservation functions as a complete or part replacement for traditional organic acid based liquid preservative products.
-Batch 1: untreated feed.
-Batch 2: ammonium propionate and propionic acid at 400gr/tn.
-Batch 3: cimenol ring at 400gr/tn.
Results in pig feed:
Results in ruminant feed:
Results in poultry feed:
Cimenol ring reduced from 95% to 100% the count of microorganisms compared to the control batch.
Cimenol ring reduced from 65% to 100% the count of microorganisms compared to the organic acids used.
To summarise, Cimenol ring represents a valid alternative to the organic acids.