Investigators from the University of Dublin have demonstrated in vitro, that some strains of lactobacillus and Bifidobacterium longum reduce the association and internalization of Campylobacter jejuni and they have suggested that this combination of beneficial bacteria could be used in the prophylaxis for human campylobacteriosis.
The same group of investigators, has also demonstrated, by publishing an article in May 2010 at the Journal of Medical Microbiology, that the intestinal mucus of birds inhibits the internalization of Campylobacter jejuni and they have asserted that the mucina in birds, the main component of intestinal mucus, is responsible for the inhibition of the virulence of Campylobacter jejuni. In this last study, investigators confirmed in vitro that the intestinal purified mucina reduces the union and internalization in cells HCT-8 and it depends on the place of origin of the mucina. Differences in the composition of the mucina in birds can contribute to the differential result of infections for Campylobacter both in this species and the human beings.
This information, associated to the knowledge that in birds the composition of portion is an important factor for the intestinal microflora and the establishment of microbial communities, will allow new investigations that maybe will convert shortly to the manipulation of portion composition, the microbial communities and the composition of the mucina, in natural tools to keep the balance in intestinal microenvironment and to impede the colonization and proliferation of harmful bacteria.
Please note this new line of investigation will be useful to prevent not only campylobacter but other enteropathogens.